TUMIVONO 20MG
$49.00$69.00
Vonoprazan 20mg
TUMIVONO (Vonoprazan) has high affinity and slow clearance from gastric parietal cells.
TUMIVONO (Vonoprazan) produces rapid, profound and sustained suppression of
gastric acid secretion for over 24 hours.
TUMIVONO is superior to conventional PPIs.
Description
TUMIVONO (Vonoprazan) is a novel orally active potassium competitive acid blocker (P- CAB)
PCABs represent an alternative to proton-pump inhibitors for the treatment of acid related
disorders. Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic
polymorphisms and do not require acid-resistant formulations. 1
Furthermore, vonoprazan is 350-times more potent than the proton-pump
inhibitor lansoprazole, thanks to its ability to accumulate in the gastric corpus mucosa,
specifically in the parietal cells. 2
It binds and inhibits H+, K+-ATPase at the final step in the acid secretory pathway in
gastric parietal cells.
Has a rapid, long lasting and reversible inhibition of the gastric H+, K+-ATPase.
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